![]() Published by Oxford University Press on behalf of the American Burn Association. It is the patients' (after extensive education) and clinicians' choice, level of experience, and availability of products in praxis that will guide the decision as to which the product is used individually on which patient. ![]() An international consensus has concluded that an antimicrobial action is indicated to help reduce bioburden. This silver foam dressing can inactivate wound relevant pathogens (bacteria and fungi) within 30 minutes, as shown in vitro 1. Patient satisfaction and comfort seems better with Biobrane™ although not reflected within the end outcome of the healed wound. Mepilex Ag is our versatile antimicrobial foam dressing designed for low to medium exuding burns and wounds. Mepilex® Ag achieved faster re-epithelialization and better cost effectiveness. The aim of this study was to assess the magnetic resonance (MR) safety and compatibility of this dressing, according to the standard requirements of the American Society for Testing and Materials (ASTM). Economic analysis showed that there was a 99%, 71%, and 53% probability that Mepilex® Ag dominated (cheaper and more effective) Biobrane™, Acticoat™, and Aquacel® Ag, respectively. Aquacel Ag is an ionic silver-containing barrier dressing that is able to absorb large amounts of wound exudate. Adjusting for sex, age, smoking status, burn mechanism, TBSA, and first aid adequacy, Mepilex® Ag had a reduced time to re-epithelialization compared to Biobrane™ (IRR: 1.26 95% CI: 1.07-1.48, P <. One hunderd thirty-one partial thickness burn wounds in 119 patients were randomized. ![]() Dominance probabilities between treatment arms were calculated from bootstrap resampling trial data. Incremental cost-effectiveness ratios were calculated based on dressing costs. Get Surgical Dressing at lowest price ID. Primary endpoint for analysis was >95% re-epithelialization. Amos Health Tech - Offering Convatec Aquacel Ag Hydrofiber Dressing at Rs 6500/piece in Chennai, Tamil Nadu. Adults with partial thickness burns meeting inclusion criteria were randomized to either Biobrane™, Acticoat™, Mepilex® Ag, or Aquacel® Ag. The presented results could be of interest to clinicians managing wounds.Ĭhlorhexidine acetate lysostaphin manuka honey povidone-iodine silver wound dressing materials.This prospective, randomized controlled trial study compared the effects of four dressings for adult partial thickness burns, focusing on re-epithelialization time and cost effectiveness. Some important differences in the antimicrobial potential of investigated materials have been found. Results revealed that its activity against Staphylococcus aureus was comparable to the most active wound dressings impregnated with silver or inadine. Mepilex Border Ag (Molnlycke) View adult BNF View SPC online View childrens. In addition, we also tested the anti-staphylococcal activity of a biopolymer material impregnated with lysostaphin. The Medisorb Silver Pad, containing silver, and Bactigras, which contains chlorhexidine acetate, revealed much lower antimicrobial activity, particularly noticeable in the time-killing assay. High activity against all tested bacteria, but only in the disc diffusion assay, was observed for Algivon, which contains manuka honey. However, 24 hours' includation was required for complete elimination of the cells of this bacteria strain. High effectiveness against Escherichia coli was also demonstrated for Silvercel. In the case of Aquacel Ag, 24 hours' incubation resulted in complete elimination of the cells of both Gram-negative bacteria, Escherichia coli and Pseudomonas aeruginosa.The Escherichia coli cells were killed after only four hours' treatment. Silvercel, Aquacel Ag and Melgisorb Ag, which also contain silver, also exhibited a satisfactory level of activity. The same results were obtained for a povidone-iodine containing dressing, Inadine, though its activity was lower in the disc diffusion assay. Incubation for four hours of a 10x10mm 2 piece of this material in 10ml cells suspension (concentration: 10 9-10 10CFU/ml) resulted in complete elimination of bacteria of all four strains tested. The materials were tested against four reference strains of bacteria: Staphylococcus aureus (PCM 2051), Staphylococcus epidermidis (PCM 2118), Pseudomonas aeruginosa (ATCC 27853), and Escherichia coli (K12), using the disc diffusion-like method and a time-killing assay.įor both experiments, the highest activity against all four tested strains of bacteria was observed in the case of Mepilex Ag, which contains silver as an antibacterial agent. The aim of our study was to examine the antimicrobial potential of eight selected, commercially available wound dressings containing different antimicrobial agents: silver, chlorhexidine acetate, povidone-iodine, and manuka honey.
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